TA Instruments Nano ITC Series Getting Started Manual

TA Instruments Nano ITC Series Getting Started Manual Manual pdf 12 page image

Page 12 Nano ITC Getting Started GuideSystem Components• Nano Isothermal Titration Calorimeter• Personal computer (optionally available from TA Instruments)• ITCRun and NanoAnalyze software• Power cord• Getting Started Guide (this manual)• Data Collection and Analysis Software• 1 each 2.5-mL filling syringe with 16-gauge, 8-inch long needle (Standard Volume ITC)• 1 each 0.5-mL filling syringe with 16-gauge, 8-inch long needle (Low Volume ITC)• 1 each 100-μL and 250-μL syringes (with Nano ITC Standard Volume)• 1 each 50-μL syringe (with Nano ITC Low Volume)• 1 each buret drive• USB cableThe components that make up the Nano ITC system are briefly described in the following sections.Measuring UnitThe measuring unit includes the calorimeter block and two non-removable reaction vessels (sample andreference cells). Access tubes extend downward from inside the buret mounting cavity on the top of thecalorimeter. The access tubes serve as conduits for the filling syringe, titrant delivery, and reference needle.They also provide for titrant equilibration and as a thermal barrier to the environment outside thecalorimeter.Figure 4 Nano ITC measuring unit.The Nano ITC utilizes a differential power compensation design. Semiconducting thermoelectric devices(TED) are used for temperature control and to detect temperature differences between the sample andTED-controlledblockThermalshieldReferencecellSample cellControl heaterDT