Please refer to the following procedure for the cooling of vaccines: Install the isolation inserts into the device. (See also section “Installation of the Isolation Inserts”). After setting into operation the device will have to operate for a minimum of 24 hours, until thetemperature suitable for the storage of vaccines is reached. To avoid a further extension of thatperiod, the device must be operated empty, i.e. without Icepacks, and without vaccines. Use the thermometer enclosed to check the temperature of the cooling section after about 24 hours.For storage of vaccines the temperature should be within a range between +1°C and +8°C. Do notstore any vaccines, until the device is performing a stable operation at the required operatingtemperature. Keep checking the temperature and use the thermostat switch to correct it, if necessary. Perform a daily temperature check and record the temperature when the device is in operation.Useful Notes: Store your vaccines such that air can circulate between the individual packages. Open the lid of the device just as often and just as long as absolutely necessary. Keep the device tidy inside. Thus, you can avoid unnecessarily extended opening periods. Fill the Icepacks with cold, clean water. It is recommended that a 24 hour pre-cooling be undertaken until the Icepacks are inserted. Do not make attempts to cool Icepacks during the cooling phase immediately following the settinginto operation of the device. Best transmission of the cooling temperature can be obtained, when the Icepack is pressed to theevaporator as hard as possible. The refrigerator should be cleaned inside and outside before it is set into operation and afterwards inregular intervals. Use lukewarm water with a mild cleaning agent. Abrasive or caustic cleaning agents, steel wood,scouring sponges, or chemical cleaning agents should in no case be used. After the cleaning is finished, the device should be dried properly. The interior section of therefrigerator must be free of water and humidity. If the device shall be taken out of operation for a longer period, the inner and outer containers shouldbe cleaned and the lid should be left open a small gap, to avoid unpleasant smells.Due to the humidity of the ambient air, a layer of ice will form gradually on the evaporator. As a result ofthe unit construction, that ice layer will at first form at the left side of the evaporator. If that ice layer isthicker than 1 cm, the cooling capacity of the device will be impaired. In such a case the device must bedefrosted. Remove the vaccines, Icepacks and isolation inserts. Store these materials in another pre-cooledrefrigerator. Switch off the device – if operated electrically, unplug the mains cable; if operated with gas, shut offthe gas supply valve at the gas cylinder. Open the lid and wait until the ice has completely melted. DO NOT MAKE ATTEMLPTS TO REMOVE THE ICELAYER USING A KNIFE OR ANY OTHER TOOL. After defrosting the interior of the device must be completely and properly cleaned and dried. DO NOTUSE ANY HEATING DEVICES TO DRY THE DEVICE. Open the lid of the device just as often and just as long as absolutely necessary, in order to preventthe unit from humidity penetrating into the interior.Page 6VACCINE COOLINGICEPACK FREEZINGCLEANINGDEFROSTING