28Chapter 6: Maintaining Your Filtered PCR Enclosurewhen downflow velocity drops below the recommended 30-65 fpmvelocity and the speed control is adjusted to full speed. ReplaceHEPA filter if it fails the HEPA Filter Leak Test in Chapter 6.How to Install a New HEPA FilterNOTE: Only a qualified certifier should service the HEPA filter.After the HEPA filter is replaced, the enclosure MUST becertified. See Figure 6-1.1. Unplug the enclosure and remove the prefilter located ontop.2. Remove the front panel by loosening the two screws thatsecure it.3. Using a 9/16" deep socket, loosen the filter clamp boltslocated on top. Refer to Figure 6-1.4. With the clamp bolts loosened, the HEPA filter-clampingframe should be clear of filter. Carefully pull the filterstraight out of the enclosure and discard properly.5. Cover the surface of the new HEPA filter gasket with alight coating of silicone grease, if desired.6. Install the new HEPA filter by pushing it straight into thecabinet, ensuring that it is correctly oriented with the gasketfacing down on the exhaust side of the enclosure.7. Tighten the clamp bolts uniformly until the filter gasket isproperly compressed against the frame. Inspect the sealthoroughly before proceeding.8. Reinstall the front panel and prefilter.9. Plug the enclosure in and have it check for leaks anddownflow velocity.CAUTION: The filter clamp bolts should only be tightenedenough to ensure a proper seal at maximum tightness. Thefilter gasket should be compressed 50% or less.