Labconco FreeZone Triad 7940010 Series User Manual
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Contents
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Product Service 816-333-8811 or 1-800-522-7658 1Original instructionsCHAPTER 1INTRODUCTIONCongratulations on your purchase of a Labconco FreeZone® Triad™ Freeze DrySystem, which is designed for laboratory lyophilization procedures. Therefrigerant used in the refrigeration system is HCFC-free so it will not endangerthe environment. The unit is easy to install and maintain. Proper care andmaintenance of this product will result in many years of dependable service.Intended UseThe Labconco Freeze Dryers described in this manual are intended for laboratoryuse to facilitate the lyophilization process.Freeze Dry ProcessFreeze drying is an important process in sample preparation and for the preservationand storage of biologicals, pharmaceuticals and foods. Of the various methods ofdehydration, freeze drying (lyophilization) is especially suited for substances that areheat sensitive. Other than food processing (e.g., coffee, whole dinners), freeze dryinghas been extensively used in the development of pharmaceuticals (e.g., antibiotics) andpreservation of biologicals (e.g., proteins, plasma, viruses and cell lines). Thenondestructive nature of this process has been demonstrated by the retention ofviability in freeze dried viruses and microorganisms.Freeze drying is a process whereby water or other solvent is removed from frozenmaterial by converting the frozen water directly into vapor without theintermediate formation of liquid water. The basis for this sublimation processinvolves the absorption of heat by the frozen sample in order to vaporize the ice;the use of a vacuum pump to enhance the removal of water vapor from the surfaceof the sample; the transfer of water vapor to a collector; and the removal of heat bythe collector in order to condense the water vapor. In essence, the freeze dryprocess is a balance between the heat absorbed by the sample to vaporize the ice,and the heat removed from the collector to convert the water vapor into ice. |
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