Document: 333D012G5-18-2007- 26 -Replacing the HEPA FiltersWhen the certifier can no longer set the cabinet air flows to within ±5% FPM of the nominal set point byadjusting the speed control and/or balancing damper then it may mean the filters are loaded with particles and must bereplaced. If the filters are damaged, they will also need to be replaced.Before any seal panels are removed, the cabinet should be decontaminated. The filters are sure to have collectedmicroorganisms and other potentially harmful particles generated in the work area during their lifetime, andmaintenance personnel should not allow themselves to be exposed. It should also be remembered that a specificgaseous decontamination might work against microorganisms, but not against chemical agents. Where chemicals arepresent, consult an industrial hygienist or other qualified person.A chemically contaminated filter must be handled with caution. Clothing and/or breathing apparatus should beused to protect personnel as necessary to reduce the hazard. It is advisable to seal the contaminated side of the filterby taping a plastic sheet or cardboard over the face before removal. This should minimize the number of particlesshaken loose from the filter. Once removed, the filter should immediately be sealed in a chemical hazard bag and thendisposed of safely in accordance with environmental regulations.After filter replacement has been completed, the cabinet and the room should be cleaned and decontaminated in amanner consistent with the nature of the hazardous material. The cleaning materials, along with the protective gearand clothing should be properly disposed.HEPA filters are very easily damaged, and you will want to use great care in handling so as to avoid injury to thefilter media and gasket surfaces. When installing the new filters, it is a good idea to tape a piece of cardboard over thefilter media to give protection against dropped wrenches or misdirected fingers. Of course, you'll need to make surethat the cardboard is removed before the access panels are re-installed. Inspect the filters carefully before and afterinstallation. A broken or damaged filter is worthless.For detailed instructions on changing the filters, see the following two sections.