Idexx SediVue Dx Operator's Manual

Also see for SediVue Dx: User guide

Idexx SediVue Dx Operator's Manual Manual pdf 14 page image

14Understanding your resultsIn addition to determining results, the SediVue Dx* convolutional neural network verifies image andresult quality with each run. If the image quality cannot be verified or if confirmatory methods shouldbe considered, a message will appear at the bottom of your results indicating possible next steps.DilutionsWhen a urine sample is crowded and the edges of the elements overlap, the SediVue Dxconvolutional neural network may have difficulty discerning the elements from one another. Dilutingthe urine sample will help spread the elements apart for easier identification and classification.This section will help you identify when dilutions may be necessary both preanalysis andpostanalysis and provide you with insight to help reduce additional dilution work-flow steps.Note: Diluting a urine sample may affect the pH and osmolality of the sample and lead to changesin cellular appearance and the presence of crystals.Preanalysis dilutionsThere are times during the physical evaluation of the clarity and color of urine samples when it’sobvious that samples will be crowded with cells, bacteria, debris, or crystals (e.g., gross hematuria).This evaluation will aid in determining if a dilution should be considered preanalysis.Use the guidelines below to determine if the sample should be diluted prior to running it on theSediVue Dx analyzer.Note: It’s always good practice to remove an aliquot of the original sample in case additionaltesting is needed.Does the color of the samplesuggest evidence of hematuria?Red Dark red BrownDoes the clarity of thesample suggest highamount of cells, bacteria,crystals, or debris?VerycloudyOpaqueConsider a 1:5 dilution with 0.9% normal saline, remix the diluted sample, and rerun.Postanalysis dilutionsWhen a “crowded” sample is run on the SediVue Dx analyzer, your semiquantitative results may besuppressed and you will be prompted to consider a dilution. When this occurs, an image review isessential to determine the appropriate next steps.• If the images provide clinical insight, a simple annotation to the patient record may be appliedand you may be able to move on without a dilution.1• If the images do not provide clinical insight, diluting the urine sample will help to spreadthe elements apart for more accurate analysis. The dilution ratio will vary depending onthe severity of the crowding in the sample. Follow the guidelines below to determine if apostanalysis dilution may be helpful.