Idexx SediVue Dx Operator's Manual

Also see for SediVue Dx: User guide

Idexx SediVue Dx Operator's Manual Manual pdf 18 page image

18CrystalsCrystals can come in a variety of different shapes, sizes, andpresentations. Urine pH, specific gravity, sample preparationand handling, and drugs can all play a part in crystal formation.Crystals in small numbers (e.g., struvites) may be normalfor some dogs but others (e.g., cystine) may signify diseaseprocesses. The following Smart Flags are designed to providefurther clinical insight into the presence of crystalluria.Suspect crystalluria. Review images to confirm.When the sum of all crystal types is ≥1/HPF but no specificcrystal parameter has met the minimum threshold of 1/HPF to be reported and tagged, then thesuspect crystalluria flag will be triggered. All crystal types will still be reported as “none to rare.”Example: STR 0.3/HPF (None to Rare, no tags)CRY 0.75/HPF (None to Rare, no tags)------------1.05/HPF => Suspect crystalluria flagCrystalline debris detectedCrystalline debris can be abundant and variable in size andpresentation in some samples. Due to background density, thepresence of large amounts of crystalline debris can affect theidentification of other formed elements in the sample.This flag is displayed when crystalline debris has beendetected by the algorithm. The neural network algorithm hasbeen trained to exclude crystalline debris from the unclassifiedcrystal (CRY) category. When this flag is present, users will benotified so they can be more discerning of the bacteria resultas very small particles of debris can resemble bacteria.Urine protein:creatinine (UPC) ratioWhen the Consider evaluation of urine protein:creatinine ratio message appears, the urine chemicalresults indicate the presence of protein. A UPC ratio can be used to quantify protein loss in theurine as it is unaffected by urine volume or concentration. It has been incorporated into the IRISGuidelines on Staging and Treatment of Chronic Kidney Disease (CKD) as an important monitoringtool at all stages. A UPC should be performed after urinalysis with sediment examination. It is notrecommended for use if there is an “active sediment” as inflammatory conditions in the urinary tractwill increase protein and negate the usefulness of the ratio.What if there is active sediment?When active sediment is detected, the Recommend reevaluate proteinuria after resolution of activesediment message appears.First, resolve the infection. Once the sediment becomes inactive, consider running a UPC toquantify protein loss.Understanding Your Results