161However, none of the studies can answer questions about long-term exposures, since the average period of phone use in thesestudies was around three years.What research is needed to decide whether RF exposurefrom wireless phones poses a health risk?A combination of laboratory studies and epidemiological studiesof people actually using wireless phones would provide some ofthe data that are needed. Lifetime animal exposure studies couldbe completed in a few years.However, very large numbers of animals would be needed toprovide reliable proof of a cancer promoting effect if one exists.Epidemiological studies can provide data that is directlyapplicable to human populations, but ten or more years' follow-up may be needed to provide answers about some health effects,such as cancer.This is because the interval between the time of exposure to acancer-causing agent and the time tumors develop - if they do -may be many, many years. The interpretation of epidemiologicalstudies is hampered by difficulties in measuring actual RFexposure during day-to-day use of wireless phones. Manyfactors affect this measurement, such as the angle at which thephone is held, or which model of phone is used.What is FDA doing to find out more about the possiblehealth effects of wireless phone RF?FDA is working with the U.S. National Toxicology Program andwith groups of investigators around the world to ensure that highpriority animal studies are conducted to address importantquestions about the effects of exposure to radio frequencyenergy (RF). FDA has been a leading participant in the WorldHealth Organization international Electromagnetic Fields (EMF)Project since its inception in 1996.An influential result of this work has been the development of adetailed agenda of research needs that has driven theestablishment of new research programs around the world. TheProject has also helped develop a series of public informationdocuments on EMF issues.FDA and Cellular Telecommunications & Internet Association(CTIA) have a formal Cooperative Research and DevelopmentAgreement (CRADA) to do research on wireless phone safety.FDA provides the scientific oversight, obtaining input fromexperts in government, industry, and academic organizations.CTIA-funded research is conducted through contracts toindependent investigators. The initial research will include bothlaboratory studies and studies of wireless phone users. TheCRADA will also include a broad assessment of additionali897 Vegas.book Page 161 Monday, July 19, 2010 12:26 PM