CIRRUS HD-OCT User Manual 2660021169012 Rev. A 2017-12Posterior Segment 8-21cáÖìêÉ=UJNQ=^Çî~åÅÉÇ=omb=^å~äóëáë=Ó=pÅêÉÉå=OOn Screen 2 (Figure 8-14), the sub-RPE illumination segmentation is overlaid on the RPEElevation Map. The sub-RPE illumination segmentation is shown with an outline. Thisimage shows the fovea location with a dot marking and a circle corresponding to 3 mmand 5 mm diameter circles centered on the fovea. This image is superimposed on top of theFundus image.Use the caliper to measure distances on the RPE Profile Map.NOTE: Caliper measurements are not saved!Calculated values are of the current scan minus the prior, as well as the percent change inelevations and illumination since the previous scan.The volume of RPE elevations, as well as the area and distance of the sub-RPE illuminationaround and from the Fovea respectively, are shown. If no sub-RPE illumination is seen inthe circle, the value shown is 0.0. A warning message will appear if the 5 mm circleextends outside of the scan window or if the scan is too low in the B-scan window.Advanced RPE Analysis may occasionally identify RPE elevations or areas of sub-RPEillumination in normal subjects. In a post-hoc analysis of 115 subjects from the diversifiednormative database, the software identified RPE elevations in the 5 mm circle in 2.6% ofthe subjects, with a mean of 0.006 mm 2 for area and 0.0002 mm 3 for volume. In the sameanalysis, the software identified areas of sub-RPE illumination in 6.1% of the subjects, witha mean area of 0.08 mm2 .NOTE: Calculated differences do not consider test-retest variability.
